Electrical vagus nerve stimulation for the treatment of chronic heart failure

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Chronic vagus nerve stimulation: a new and promising therapeutic approach for chronic heart failure.

AIMS In chronic heart failure (CHF), reduced vagal activity correlates with increased mortality and acute decompensation. Experimentally, chronic vagus nerve stimulation (VNS) improved left ventricular (LV) function and survival; clinically, it is used for the treatment of drug-refractory epilepsy. We assessed safety and tolerability of chronic VNS in symptomatic CHF patients, using a novel imp...

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Intermittent Vagus Nerve Stimulation Reflexively Modulates Heart Rate Variability in Rats with Chronic Ischemic Heart Failure

Heart disease is the leading cause of death in the developed world. Despite major strides made in the past decade regarding the treatment and prevention of heart disease, cardiac injury due to acute myocardial infarct (MI) remains a difficult and complicated problem to solve. When enough tissue damage occurs in the myocardium, the ability of the heart to circulate blood is reduced and the organ...

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Vagus nerve stimulation in the treatment of nervous system disease: a review article

The vagus nerve (VN), the longest cranial nerve and an essential part of the parasympathetic system, connects the central nervous system to respiratory, cardiovascular, immune, gastrointestinal, and endocrine systems and is involved in the maintenance of homeostasis by controlling these systems. Vagus nerve stimulation (VNS) is related to any method that would stimulate the vagal nerve via elec...

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Vagus nerve stimulation therapy randomized to different amounts of electrical charge for treatment-resistant depression: acute and chronic effects.

BACKGROUND Major depressive disorder is a prevalent, disabling, and often chronic or recurrent psychiatric condition. About 35% of patients fail to respond to conventional treatment approaches and are considered to have treatment-resistant depression (TRD). OBJECTIVE We compared the safety and effectiveness of different stimulation levels of adjunctive vagus nerve stimulation (VNS) therapy fo...

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Vagus nerve stimulation therapy

Over the past 5 years, and especially within the last year, there has been a rapid expansion of vagus nerve stimulation (VNS)-related preclinical research, as well as clinical studies in indications other than epilepsy. The research advances in understanding VNS are occurring in the midst of a blossoming of other forms of therapeutic brain stimulation, such as electroconvulsive therapy (ECT), t...

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ژورنال

عنوان ژورنال: Cleveland Clinic Journal of Medicine

سال: 2011

ISSN: 0891-1150,1939-2869

DOI: 10.3949/ccjm.78.s1.04